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Test tube encyclopedia websiteIn vitro fertilization in the United States

How long does it take to complete the entire process of IVF in the United States?

Test tube encyclopedia website 2026-04-10 13:55:58 In vitro fertilization in the United States Read: 8134 times

πŸ•’ How long does it take to have IVF in the United States? "- This is the first question asked by almost all families preparing to go to the United States to start assisted reproduction. The answer is not simply "30 days" or "3 months", but a timeline woven together by medicine, law, logistics, finance, and emotions. Today, we will break down this timeline into 8 stages and 46 key nodes, and explain them all at once using tables, text, and emojis. After reading it, you can turn 'vague expectations' into' executable schedules' and 'listening to others' into' doing your own calculations'.

πŸ—ΊοΈ 1、 Conclusion: On average, it takes 107-168 days (approximately 3.5-5.5 months)

From the first day of menstruation in China to the day of embryo transfer in the United States, the average is 107 days; If combined with initial hysteroscopy, genetic testing, accumulated embryos, immune regulation, or intrauterine adhesion treatment, the maximum duration is 168 days. Please take a screenshot of the overview table below and save it for easy reference at any time.

stage Domestic or American Starting and ending days core mission Is it necessary to go to the United States Common variables
β‘  Pre inspection in China Menstrual Day 1 to Day 20 Hormones, ultrasound, infection, genetics, semen, hysteroscopy ❌ Hysteroscopy reveals adhesion+7-14 days
β‘‘ Remote video online Day21~Day35 First visit with the attending physician, plan and medication schedule ❌ Time difference, supplementary examination+5 days
β‘’ Visa& itinerary in China Day36~Day50 B1/B2 reservation EVUS、 Booking an apartment and purchasing insurance ❌ Face to face interview checked+15 days
β‘£ Promoting emissions and; monitor America Day51~Day64 Go to the United States, file, get a booster shot, and undergo 4-5 ultrasounds βœ… Uneven follicles+3 days
β‘€ Egg retrieval& fertilization America Day65~Day67 Intravenous anesthesia for egg retrieval ICSI、 Observation of Fertilization βœ… Low fertilization rate β†’ Remedial ICSI+1 day
β‘₯ Embryo culture America Day68~Day74 Day 3 β†’ Day 5/6 blastocyst, photo, rating βœ… Slow development β†’ reaching standard on Day 7+1 day
⑦ Genetic screening America Day75~Day89 Biopsy, whole genome amplification NGS、 wait for the report βœ… Re inspection+7 days
β‘§ Cryotransplantation America Day90~Day107 Endometrial preparation, thawing, transplantation, blood test βœ… Endometrium<7 mm β†’ Cancel+21 days

🧩 Explanation: If 2 cycles of embryos need to be accumulated before transplantation, the total duration is approximately 150 days; If intrauterine adhesions are treated with immunotherapy after surgery, it will take approximately 168 days.

πŸ₯ 2、 Hospital selection and first arrival time in the United States

The Centers for Disease Control and Prevention (CDC) in the United States releases the "Assisted Reproductive Technology Clinic Reports" once a year. The latest 2022 version of data shows that the average live birth rate of 448 clinics in the United States is 33.1% (<35 years old from egg fresh cycle). The following 8 top institutions located in California, New York, and Boston, with a cycle size of β‰₯ 500 and a live birth rate of β‰₯ 55%, are often prioritized for international patients:

sort English name Chinese idiomatic expressions City of residence 2022 live birth rate%(International Chinese Assistant
1 INCINTA Fertility Center IFC IVF Center in the United States Torrance, Los Angeles 68.4 βœ… 7 Γ— 24 WeChat
2 Reproductive Fertility Center RFC Reproductive Center in the United States Los Angeles Corona 65.7 βœ… 7 Γ— 24 WeChat
3 HRC Fertility HRC Reproductive Medicine Group Pasadena 64.1 βœ…
4 SCRC Southern California Fertility Center Beverly Hills 62.9 βœ…
5 RMA of New York New York RMA Manhattan, New York 61.8 βœ…
6 Boston IVF Boston IVF Boston 60.5 βœ…
7 Shady Grove Fertility Shady Grove Fertility Center Maryland 59.3 ❌
8 CCRM Colorado CCRM Colorado Denver 58.7 βœ…

πŸ›‚ It is recommended to schedule your first trip to the United States on the 1st to 3rd day of your menstrual cycle. You can have your blood drawn and ultrasound taken on the same day and enter the week directly, saving 14 days of waiting time.

πŸ§ͺ 3、 Stage decomposition: What do you do every day?

Below is a schedule of 107 days divided into "copying homework" sections, with time on the left and landing actions and pit avoidance prompts on the right.

Stage 1 Pre inspection (domestic, 20 days)

Day1 During menstruation, FSH, LH, E2, PRL, TSH should be taken on the same day; Negative ultrasound measurement of antral follicle count (AFC).
Day2-3 Take a photo of the blood report and send it to the Chinese assistant at the IFC IVF Center in the United States. The assistant will reply within 12 hours whether it is qualified.
Day4-10 Make AMH, blood type, blood routine, blood coagulation, liver and kidney function, hepatitis B, syphilis HIV、 Hepatitis C, Mycoplasma, Chlamydia, Neisseria gonorrhoeae, electrocardiogram, chest X-ray.
Day11-15 Male semen analysis+deformity rate+DNA fragments+infection; If the fragmentation rate is greater than 25%, open the antioxidant for 2 months.
Day16-18 Hysteroscopy: Examining endometrial polyps, adhesions, and chronic endometritis; Obtain CD138 immunohistochemistry during surgery.
Day19-20 Package all PDFs and send them to a doctor in the United States to schedule a video interview time (usually 15 hours Beijing/Los Angeles time difference, choose 9 pm later).

Stage 2: Remote video+customized plan (online, 15 days)

Day21 Zoom first visit: Dr. James P. Lin (INCINTA) or Susan Nasab, MD (RFC) will appear in person for 30 minutes.
Day22 Received the electronic version of the "treatment agreement+cost list" from the US, including medication costs, laboratory tests, anesthesia ICSI、 Nourishing capsules and freezing.
Day23-25 Domestic lawyers review agreements, confirm liability clauses, refund rules, embryo ownership, and divorce/death disposal.
Day26 Sign, pay the first 30% deposit by credit card, and have the medication (Gonal-F, Menopur, Cetrotide) delivered to China via express delivery from the US.
Day27-35 Starting from the 21st day of menstruation, the menstrual cycle will begin to decline (Lupron or oral contraceptives), and an appointment for a face-to-face interview will be made at the same time.

Stage 3 Visa& Travel itinerary (domestic, 15 days)

Day36 Fill in DS-160 and schedule a face-to-face interview; Reason for selecting "medical treatment", materials: appointment letter, doctor invitation letter, asset proof.
Day45 Face to face visa in Beijing/Shanghai/Guangzhou, approved on the spot, passport will be returned by EMS within 3 working days.
Day46-50 Booking an apartment (recommended Torrance sea view apartment, 5-minute walk to INCINTA, with kitchen for cooking Chinese medicine); Buying travel insurance includes IVF complications.

Stage 4: Promoting Drainage& Monitoring (USA, 14 days)

Day51 Arrive in LA, answer the "medical" purpose upon entry, present a doctor's invitation letter, and stay for 6 months.
Day52 At 8:00 am, blood (E2, LH, P4) will be drawn from INCINTA and a negative ultrasound will be performed. The nurse will teach to administer the first dose of Gonal-F 300 IU.
Day53-58 Inject at the same time every day, and return to the hospital for a follow-up examination on the 4th day. The doctor will adjust the dosage according to the follicle diameter line.
Day59 When β‰₯ 2 follicles β‰₯ 18 mm and E2 β‰₯ 2500 pg/ml, trigger the overnight needle (Ovidrel 250 ΞΌ g) and retrieve the eggs strictly after 36 hours.
Day60 Fasting at 0:30, intravenous anesthesia for egg retrieval at 8:30, completed in 10 minutes; On the same day, my husband had synchronized ejaculation.

Stage β‘€ Laboratory& Fertilization (USA, 3 days)

Day61 Embryologist ICSI fertilized the embryo, and after 16 hours, the prokaryotic (2PN) was observed. The Day1 report was sent the next day.
Day62 On Day 3, embryos with 6-8 cells were photographed and sent to a WeChat group. The doctor decided to continue culturing the embryo or immediately transplant it (in rare cases).
Day63-64 Day5/6 blastocysts, according to Gardner's rating, β‰₯ 3BB enter the biopsy assembly line.

Stage 6 Genetic Screening (USA, 15 days)

Day65 Laser biopsy is performed on 5-8 trophoblast cells, and the embryos are vitrified and frozen. The samples are sent to NGS.
Day66-74 Laboratory amplification, library construction, and computer setup take an average of 7 working days; Report should be sent to the email address, marked as diploid/chimeric/non diploid.
Day75-89 If there is a "30% chimerism", re inspection is required, with an additional 7 days; If there are β‰₯ 4 diploid cells, they can enter the month of transplantation.

Stage ⑦ Cryotransplantation (USA, 18 days)

Day90 During menstruation, start supplementing with 2mg bid of JiaLe every 4 days until the endometrium is β‰₯ 8mm.
Day98 Return to the hospital for ultrasound, if the standard is met, add 50 mg of progesterone oil IM QD, and transplant on the 6th day.
Day104 Thaw one intact blastocyst, complete in 5 minutes, ultrasound-guided, no anesthesia, bed rest for 30 minutes, return to the apartment.
Day111 On the 7th day after transplantation, Ξ² - HCG levels of β‰₯ 50 IU/L were detected as initial success; Double by β‰₯ 120 IU/L on the 9th day.
Day118 Yin ultrasound shows gestational sac and fetal heart rate, officially graduated, transferred to OB (obstetrician).

πŸ’° 4、 Cost time dual axis: how much money is spent and how many days are spent completely synchronized

Many people only ask about "success rate" but ignore "cash flow". Clinics in the United States require 'pay by node', and if payment is delayed, the laboratory will suspend cultivation. We have merged the "timeline" and "expense axis" to facilitate your synchronized preparation of funds.

Calendar days milestone payables INCINTA Reference USD RFC Reference USD Payment tools
Day26 Sign the agreement deposit 6,500 6,000 Visa/Master
Day52 Entering the week Promoting excretion drugs+monitoring 5,200 4,800 credit card
Day60 Egg retrieval day Anesthesia+Laboratory 9,800 9,500 credit card
Day64 Nurturing bag completed blastocyst culture 2,400 2,200 credit card
Day75 genetic screening NGS each 700Γ—4=2,800 650Γ—4=2,600 credit card
Day98 Before transplantation Thaw+transplant 4,200 3,900 credit card
Day118 graduate Annual freezing fee 650/year 600 per year credit card
Total (taking 4 embryos as an example) 31,550 29,600 β€”

πŸͺ™ Based on an estimated exchange rate of 7.2, INCINTA is approximately 227000 RMB and RFC is approximately 213000 RMB. Excluding airfare, accommodation, catering, and car rental.

✈️ 5、 Accommodation and Transportation: How to Minimize Non Medical Time

The subway system in Los Angeles is underdeveloped. It is recommended to stay within 5 miles of a clinic, which can be solved by walking or taking Uber.

  • 🏨 Apartment: Marbella Apartment (Torrance), one bedroom, one living room with kitchen for $135 per night, 8 minutes' walk to INCINTA.
  • πŸš— Car rental: Hertz weekly rent of $280, including insurance; But on the day of egg retrieval, self driving is not allowed and Uber is required for round trips.
  • πŸ›’ Supermarket: Whole Foods is a 6-minute walk away, where you can buy organic vegetables, coconut water, and avocados, which are suitable for promoting high protein diets.
  • πŸ“± Communication: T-Mobile Tourist Card 30 days 50 GB $50, supports WeChat video, hospital Wi Fi full coverage.

🍽️ 6、 Diet and Exercise: A Practical Checklist for Nourishing the Endometrium to 8mm

American nurses do not prescribe traditional Chinese medicine, but they provide evidence-based nutrition advice, which we have translated into a Chinese menu.

meal Ingredients (available in American supermarkets) effect alternative
breakfast Oats+Blueberries+Walnuts+Whole Milk Ο‰-3、 Vitamin E, improve blood flow Flaxseed powder replaces walnuts
lunch Salmon+quinoa+broccoli+olive oil High quality protein, coenzyme Q10, antioxidant Chicken breast meat as a substitute for salmon
dinner Beef steak+avocado+spinach+tomato Iron, folic acid, L-arginine Tofu replaces steak
snack Dark chocolate β‰₯ 70%, 2 Brazil nuts Magnesium, selenium, improve uterine blood flow Saltless almond replacement

πŸƒβ™€οΈ Exercise: From the 1st to the 8th day, promote brisk walking of 5 km. From the 9th day onwards, if the ovaries increase by β‰₯ 5 cm, switch to stretching and meditation to prevent twisting.

πŸ“„ 7、 Law and Documents: What to Do About Embryo Ownership, Divorce, Death, and Relocation?

The American clinic writes the 'worst-case scenario' into the agreement, and it takes weeks to sign it. Key terms extracted in Chinese:

  1. Embryo ownership: On the day of fertilization, it is considered as "joint property of husband and wife". In case of divorce, the family court will make a ruling, and the clinic will only follow the court's order.
  2. Death of one party: The surviving party has 100% disposal rights and can continue transplantation, freezing, or disposal without the consent of the deceased's parents.
  3. Relocation to a third country: International embryo transport company (CryoPort) can be commissioned for liquid nitrogen dry transportation, with a cost of $2200 per shipment.
  4. Failure to pay on time: If the freezing fee is overdue for 180 days, the clinic may "dispose of it according to regulations" by melting and discarding it without further notice.

🧘 8、 Emotional Management: How to Reduce Anxiety Level from 9 to 3

The biggest hidden cost of going to the United States for IVF is' emotions'. The following tools have been tested and proven effective in 300 households:

  • πŸ“± App: Headspace Meditation English Version, 10 minutes per day, reduces cortisol levels.
  • πŸ‘₯ Support group: The clinic's official WeChat group only allows patients from the same period to join the group, avoiding the comparison of "others falling for it at once".
  • πŸ“– Information boundary: Check data for a fixed 30 minute period every day, and turn off the screen at other times; Prohibit late night browsing on Xiaohongshu.
  • 🎯 Micro goal: Divide 107 days into 15 7-day small goals, such as "this week's inner membrane 6 β†’ 7 mm", and reward yourself with a cup of Peet's coffee after completion.

🧾 9、 Returning to China and prenatal check ups: How to do 'cross-border prenatal check ups' after embryo implantation

πŸ›¬ On the 28th day after transplantation (β‰ˆ Day 132), you can fly back to your home country. The airline requires that you can take the flight when you are ≀ 28 weeks pregnant. The English diagnosis certificate should be issued by the clinic. Process after returning to China:

gestational week Domestic corresponding inspection notes
6 weeks Negative ultrasound confirms gestational sac and fetal heart rate Bring American medical records, avoid repeated negative ultrasound
11 weeks NT+Early Tang Screening Notify the doctor of 'IVF conception' and correct gestational age
16 weeks Non invasive DNA NIPT US NGS report can be used as a reference
20 weeks Large displacement If twin pregnancy, increase cervical length monitoring
24 weeks Sugar tolerance IVF pregnancy diabetes risk ↑, early glucose control

πŸ“Œ 10、 Common 18 Q&A Questions; A

  1. Q: Is 2 weeks of leave enough?
    A: Only sufficient for the 'egg retrieval' stage; If including transplantation, at least 4 weeks.
  2. Q: Can I go to the United States for the first egg retrieval and the second time for transplantation?
    A: Sure, this is the most common strategy, with a total duration of 107 days that can be divided into two sections.
  3. Q: Do you administer the needle yourself?
    A: The nurse will teach, subcutaneous injection of the abdomen, self injection or asking the husband to inject, with a needle size of 31G almost painless.
  4. Q: Is egg retrieval under general anesthesia?
    A: Intravenous propofol, wake up after 10 minutes, can walk on the same day, driving is prohibited for 24 hours.
  5. Q: Is NGS harmful to embryos?
    A: Biopsy of the trophoblast layer does not affect any part of the fetus, and the miscarriage rate is consistent with not biopsy.
  6. Q: Can the inner membrane be transplanted with a thickness of 7.5 mm?
    A: β‰₯ 7 mm is sufficient, and a blood flow index greater than 2 is even better.
  7. Q: Do I need to stay in bed for 14 days after transplantation?
    A:NO! The American clinic advocates "lying down for 30 minutes after transplantation and returning home", allowing normal walking the next day, but bed rest actually reduces blood flow.
  8. Q: Can we share a room?
    A: Prohibited within 10 days after transplantation to prevent uterine contractions.
  9. Q: When will the pregnancy test stick be tested?
    A> The watermark can be detected on the 5th day after transplantation, but the official standard is still based on the 9th day blood HCG.
  10. Q: What should I do if I fail?
    A: There are remaining diploid embryos that can be transplanted again after one menstrual cycle; No embryos need to be re ejaculated.
  11. Q: Does being overweight have an impact?
    A: If BMI>35, the live birth rate will decrease by 40%. It is recommended to lose 5% of body weight first.
  12. Q: Does the man only have one ejaculation?
    A: Usually once is enough; If there are few sperm, they can be frozen and backed up in advance.
  13. Q: Can I have coffee?
    A: ≀ 200 mg of caffeine per day (1 cup of medium American).
  14. Q: Need to drink soybean milk to supplement estrogen?
    A: Normal diet is enough, and soybean milk does not enhance the intima.
  15. Q: Can I get the HPV vaccine?
    A: Complete the final injection one month before transplantation, and do not receive vaccination during pregnancy.
  16. Q: What are the inspection fees in the United States?
    A: Vaginal delivery costs between $8k and $12k, while cesarean delivery costs between $12k and $18k. It is necessary to purchase maternity insurance in advance.
  17. Q: Can I bring my embryos back to China?
    A: The law allows it, but only a few hospitals in China accept it, and it needs to be confirmed in advance.
  18. Q: How to renew the freezing fee?
    A: Annual credit card automatic deduction, $600 to $700, email reminder 30 days in advance.

πŸŽ‰ Conclusion: Make 107 days a 'replicable project'

IVF is not a gamble, but a multi-threaded project management involving time, funds, emotions, and information. When you break down each step into measurable KPIs - follicle count, endometrial thickness, estrogen, progesterone, β - HCG - you go from "passive waiting" to "active pushing". May this 4000+word long practical knowledge help you make a clear journey of 107 days with a clear mind, a watch in hand, and a path under your feet. Wishing the next B-ultrasound screen a steady and pulsating little star that belongs to you soon. 🌟

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