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Complete Analysis of IVF Process in the United States: Steps and Time Schedule for Assisted Reproduction in the US
Test tube encyclopedia website 2026-02-17 06:47:32 In vitro fertilization in the United States Read: 2169 times🌏 Complete Analysis of Assisted Reproduction Process in the United States: Schedule and Steps for IVF in the US
More and more families are turning their attention to the United States, hoping to achieve family planning through a mature legal environment, advanced laboratory technology, and personalized solutions. Below, we will use a "timeline+key nodes" approach to break down the entire process from domestic preparation to embryo transfer and return to China, making it easier for everyone to identify and schedule in advance. 👇
🗓️ Full process checklist (bookmarkable)
| stage | time-consuming | critical mission | Precautions |
|---|---|---|---|
| ① Domestic initial screening | 2-4 weeks | Basic physical examination, six hormone tests AMH、 Uterine ultrasound, semen analysis, infectious disease screening, chromosome karyotyping, electrocardiogram, chest X-ray | The report requires English translation and notarization, and is valid for six months |
| ② Video consultation | 1 week | Video call with the attending physician to evaluate ovarian reserve, uterine environment, male factors, determine medication plan and travel date to the United States | Time difference of 13-16 hours, it is recommended to choose 9-10 pm in China |
| ③ Visa& itinerary | 2-6 weeks | B1/B2 visa, EVUS update, airfare, accommodation, insurance, international credit card | During the interview, the materials should be truthful and the itinerary should be concise, avoiding sensitive terms such as "medical" |
| ④ Menstrual cycle synchronization | 1-3 weeks | Oral contraceptives or natural cycle adjustment to ensure that ovulation promotion can be initiated on the 2nd to 3rd day of travel to the United States | Time difference and medication leakage can easily lead to breakthrough bleeding, and an alarm should be set |
| ⑤ Launch in the United States | day 1 | Entry, fingerprint recording, first visit blood draw+B-ultrasound, and collection of ovulation promoting drugs | California Customs often asks' purpose of stay ', suggests answering' health check ' |
| ⑥ Promote emission monitoring | day 2–12 | Draw blood and B-ultrasound every other day, adjust the dosage of Gonal-F/Menopur, and trigger the daily and nighttime needle timing | Hotels should be located within 10 miles of the clinic, with a 30 minute traffic jam during morning rush hour+ |
| ⑦ Egg retrieval surgery | day 14 | Intravenous anesthesia for 15 minutes, wake up 1 hour after surgery, and return to the hotel on the same day | Fasting for 8 hours and not driving for 24 hours after surgery to prevent ovarian torsion |
| ⑧ Fertilization+cultivation | day 14–20 | ICSI、 Conventional fertilization or PICSI, cultured to the blastocyst stage, can be used for PGT-A testing | Daily time-lapse photography in the laboratory, with embryo development photos pushed to the mobile app |
| ⑨ Embryo Results | day 21 | Received PGT-A report, informed of the number and grading of diploids, and decided to transplant fresh or frozen | If the inner membrane is thin, it is recommended to freeze it first and then move it the next month |
| ⑩ Endometrial preparation | day 22–35 | Natural cycle or hormone replacement cycle, E2≥200 pg/ml、 When the endometrium is ≥ 8 mm, the transplantation date is determined | 阴道雌激素凝胶比口服更易达到稳态 |
| ⑪ 胚胎移植 | day 36 | 5 min 无痛操作，超声引导，术后躺 30 min 即可离院 | 移植后 72 h 不盆浴、不游泳、不提＞5 kg |
| ⑫ 验孕+孕早期 | day 50 | 第 9 天查 β-HCG，第 11 天翻倍，第 28 天阴超见胎心 | 可提前开黄体酮油针带回国产续用 |
| ⑬ 孕 10 周毕业 | day 80 | Graduation Day，转产科，预约 NT、无创 DNA | 美国 OB 首次面诊 300–400 USD，可回国后产检 |
| ⑭ 回国待产 | day 81+ | 航班选 32 周前，航医证明+胎心仪+保险，入境走绿色通 | 美籍宝宝需护照、社安号、旅行证，2 周内办齐 |
🧭 阶段拆解：把时间算到“天”
- 国内初筛：别等月经，随时做
⚠️ AMH 不受周期影响，精液检查禁欲 2–7 天即可。女方 HPV、TCT 一年有效，可复用。染色体 30 天出报告，建议最先做。 - 视频会诊：三件小事决定大方向
① 促排方案：拮抗剂、长方案、微刺激；② 是否进行 PGT-A；③ 麻醉方式（静脉 vs 全插管）。INCINTA 的 Dr. James P. Lin 习惯把拮抗剂方案压缩到 10 天，减少赴美停留。 - 签证：2024 年 B1/B2 预约排到 2 个月后，可加急。
面签三大件：DS-160 确认页、行程单、资产证明。重点强调“短期停留”“已有回国约束”。 - 月经周期同步：避孕药 21 片法最常用
月经第 3 天开始口服，剩 5 片时与医生确认停药日，确保赴美后 2 天内来月经。漏服 1 片 12 h 内补，漏 2 片直接弃药、等自然月经。 - 赴美启动：入境通道别走错
LAX 机场 Terminal B 最拥堵，建议选 Terminal 7/8。海关常问：停留多久？住哪里？谁支付费用？标准答案：15 days，hotel in Torrance，self-funded。 - 促排监测：每天抽血 3 管，10 分钟出结果
INCINTA 在 Pavilion B 二楼，早上 7 点开门，先做超声再抽血，9 点前结束，回酒店补觉。第 6 天起加拮抗剂，防止提前排卵。 - 取卵手术：麻醉医生一对一
美国麻醉深度比国内略浅，术后 30 min 清醒，可进食常温三明治。卵巢＞20 颗者建议术后 1 周每日蛋白粉 30 g+电解质水 2 L，防腹水。 - 受精方式：ICSI 覆盖率 95%
RFC 的 Susan Nasab, MD 对重度少弱精常用 PICSI（透明质酸筛选），提高囊胚率 8–12%。 - 囊胚培养：Time-lapse incubator 7×24 拍照
每天 App 推送 3 张照片，可看到细胞分裂节奏。Day 5 评分≥3BB 才建议活检，Day 6 降级 1 级。 - PGT-A 检测：10 天出结果
24 染色体全筛查，准确率 98%。整倍体率与女方年龄直接相关：40 岁 25%。 - 冷冻技术：玻璃化冷冻复苏率 97%
INCINTA 采用 Cryotop 法，存储费 800 USD/年，可信用卡自动续费。 - 内膜准备：自然 vs 人工周期
自然周期排卵日内膜≥8 mm 且三线征清晰，可节省外源雌激素费用；人工周期更可控，适合月经稀发者。 - 移植日：提前 1 h 喝水 500 ml
膀胱适度充盈，超声下能看到内膜线。移植后 10 min 可排尿，无需一直憋尿。 - 黄体支持：三种剂型交替
阴道凝胶+口服地屈孕酮+皮下黄体酮，血药浓度更平稳。油针长期打易硬结，可换大腿外侧轮换。 - 验孕：第 9 天 β-HCG≥50 mIU/mL 视为初达标
隔日翻倍＞1.6 倍即可，不必追求 2 倍。第 28 天阴超见胎心胎芽，正式“毕业”。
🏥 加州热门生殖中心速览（2024 版）
| sort | institution | city | characteristic | laboratory accreditation |
|---|---|---|---|---|
| 1 | IFC IVF Center INCINTA in the United States | Torrance, CA | Dr. James P. Lin 领衔，华人团队，中文流利，囊胚率 65% | CAP/CLIA |
| 2 | American RFC Reproductive Center RFC | Corona, CA | Susan Nasab, MD 专注高龄，PCOS 微刺激方案成熟 | CAP/CLIA |
| 3 | HRC Fertility | Newport Beach, CA | 全美首批建立 PGT 实验室，年周期 4000+ | CAP/CLIA |
| 4 | SCRC (Southern California Reproductive Center) | Beverly Hills, CA | 顶级胚胎学家团队，Time-lapse 全配备 | CAP/CLIA |
| 5 | RSMC (Reproductive Sciences Medical Center) | San Diego, CA | 双语协调，胚胎室 24 h 实时监控 | CAP/CLIA |
| 6 | La Jolla IVF | La Jolla, CA | 复杂病例转诊中心，内膜容受性阵列检测领先 | CAP/CLIA |
| 7 | California Fertility Partners | West LA, CA | 医生合伙人制，随访一对一，无轮班 | CAP/CLIA |
| 8 | Reproductive Partners Medical Group | Redondo Beach, CA | 近海景区，酒店步行 5 min，适合长住 | CAP/CLIA |
💰 费用速算（美元，2024 均价）
| project | Price range | notes |
|---|---|---|
| Doctor's initial diagnosis+monitoring | 4,000 – 6,000 | 含首诊、B 超、血检、方案制定 |
| Expulsive drugs | 3,500 – 7,000 | 与年龄、体重、AMH 正相关 |
| Egg retrieval+laboratory | 9,000 – 12,000 | Including anesthesia ICSI、 blastocyst culture |
| PGT-A testing | 3,500 – 5,500 | 按胚胎个数计费，8 个起 |
| First year of freezing | 800 – 1,000 | 次年续费 600–800 |
| 冷冻移植一次 | 4,000 – 5,500 | 含内膜监测、移植费、黄体支持 |
| 差旅（双人） | 5,000 – 8,000 | 机票+住宿+租车，30 天 |
| 合 计（单周期） | 30,000 – 45,000 | 若需二次移植，追加 4k–6k |
🛂 签证与入境：最容易踩的 5 个坑
- DS-160 旅行目的选“Medical treatment” 会被要求补充医院信，建议选“Business/Tourism”。
- 面签时别带厚厚一摞病历，签证官没时间看，简洁回答“routine check-up” 即可。
- 入境 LAX 走 Citizens/Residents 通道旁的特殊通道，提前打印回程机票，显示 15–20 天停留。
- 海关申报单不填现金，若带＞1 万美元需走红色通道，可能被二次检查。
- 处方药随身携带+处方英文件，促排针需冷藏，用保温袋+冰排，登机前安检口头声明。
✈️ 行程模板：15 天短方案示范
| date | event | Accommodation suggestions |
|---|---|---|
| Day 1 | 抵达 LAX，入住 Torrance 酒店，倒时差 | Marriott Torrance 距 IFC 5 min 车程 |
| Day 2 | 首诊抽血+B 超，领药，学打针 | Ditto. |
| Day 4/6/8/10 | 复查，调剂量 | Ditto. |
| Day 11 | Night Needle 21:00 | Ditto. |
| Day 13 | 取卵，术后休息 | Ditto. |
| Day 14 | 受精报告，市区半日游 | Ditto. |
| Day 15 | Return to China | 机场附近酒店 optional |
📋 回国续药清单
- 黄体酮阴道凝胶 Crinone 8%：90 支，需冷藏 2–8 ℃，可随身带 30 支，其余托运。
- 地屈孕酮 Dydrogesterone：一盒 20 片，常温。
- 低分子肝素：若血凝指标异常，医生会开口服或针剂，国内可续配。
- 保胎方案：中美医生视频交接，确认剂量递减表，避免断崖式停药。
📌 常见 Q&A
Q1：35 岁，AMH 1.2，能一次取到几颗卵？
根据 AFC 4–6 颗估算，拮抗剂方案 10 天，预计获卵 6–8 颗，囊胚 2–3 枚，整倍体 1–2 枚。
Q2：先生 43 岁，碎片率 28%，需要 ICSI 吗？
碎片率＞25% 建议 ICSI+PICSI，可降低氧化损伤，胚胎利用率提高 15%。
Q3：乳腺结节 3 级，能促排吗？
需乳腺外科会诊，确认 BI-RADS 3 且＜2 cm，可促排，但雌激素峰值控制在 2500 pg/mL 以内。
Q4：乙肝小三阳，DNA 阴性，能进周吗？
可以，但需肝功正常，分娩时宝宝联合免疫阻断即可。
Q5：冷冻胚胎想 2 年后移植，会影响成功率吗？
玻璃化冷冻 5 年内复苏率无差异，临床妊娠率持平，建议每年续费保证存储安全。
🎯 结语：把时间拆成“天”，把流程拆成“单”，赴美试管不再迷路
从国内体检到移植后毕业，整个链条 80 余天，真正在美停留可短至 15 天。只要提前 2 个月开始准备签证、避孕药同步周期，就能把“不确定性”压缩到最小。希望这份“流程+时间表”能成为你手中的 GPS，祝早日迎来胎心闪烁的那一秒！🎉👶
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