Test tube encyclopedia websiteIn vitro fertilization in the United States
2026 Guide to the Whole Process of IVF in the United States: Key Steps from Initial Diagnosis to Successful Implantation
Test tube encyclopedia website 2026-01-17 18:31:49 In vitro fertilization in the United States Read: 5298 timesGoing to the United States for IVF in 2026 is no longer exclusive to celebrities. From landing at Los Angeles International Airport to the first ultrasound hearing of fetal heart rate, simply breaking down 14 key nodes into a "replicable schedule" can compress a 35 day itinerary into an efficient medical trip. The following text is based on the real processes of two mainstream reproductive centers, INCINTA Fertility Center (California Torrance) and Reproductive Fertility Center (California Corona, abbreviated as RFC), combined with the latest data from the Centers for Disease Control and Prevention (CDC) in 2025, to provide a "2026 version full process guide". All times are based on menstrual Day 1, making it convenient for couples to directly compare their own cycles.
Stage 0: 90 days before departure - lock in the 'success rate' in advance
1. Domestic top three reproductive departments conduct "pre physical examination": female hormones six items (2-4 days of menstruation) AMH、 Yinchao sinus follicle count (AFC), male semen analysis (3-7 days after ejaculation). Translate the report into English and notarize it, saving $500-800 in repeat examination fees on the day of initial diagnosis in the United States.
2. Passport/US visa: B1/B2 is sufficient. When making an appointment for an interview, please bring a printed copy of the "Medical Invitation Letter" and INCINTA can issue the letter within 48 hours.
3. Proof of Funds: The mainstream price for single cycle packages in 2026 is 43000-49000 US dollars, including one port; If planning for a dual cycle, preparing $75000 to $80000 in working capital, with a bank balance of ≥ 300000 RMB, the probability of being questioned by customs will be reduced by 80%.
4. Purchase insurance: Cover America Plus or Atlas America, with a coverage amount of ≥ $100000, covering "acute complications", with a premium of approximately $280 per person per month.
5. Eat "pre processed" nutrients: For women, 200 mg of CoQ10 (ubiquinone type), 2.2 g of inositol, and 0.8 mg of compound folic acid per day 90 days in advance; for men, 1000 IU of vitamin E, 15 mg of zinc, and 200 mg of selenium per day can improve the quality of oocytes and sperm mitochondria.
Stage 1: Menstrual Day 1- Initiate Remote Consultation
Upload the pre examination report to the INCINTA encrypted port, and Dr. James P. Lin will provide a draft of the "ovulation promotion plan" within 36 hours. If FSH>12 mIU/mL or AMH<1.1 ng/mL, it is recommended to switch to a "dual stimulation" regimen: first take estrogen orally for 10 days to suppress FSH, and then enter ovulation promotion, which can increase the number of retrieved eggs by about 30%. The remote consultation fee is $350, which can be paid via WeChat/Visa.
Stage 2: Menstrual Day 19- Landing in the United States
选直飞 LAX 的航司,预留≥15小时时差缓冲。出关时回答“Medical Tourism for IVF”即可,海关通常给6个月停留期。提前在 Airbnb 订 Torrance 海景公寓,步行10分钟到诊所,月租比比佛利山庄便宜35%。
阶段3:月经Day21——美国初诊(INCINTA)
08:00 前台报到,护照+保险卡+国内病历三件套。
08:30 阴超+窦卵泡实测,护士当场告知E2、LH即时值。
09:15 见 Dr. James P. Lin,敲定最终方案:若 AFC≥15,用“拮抗剂”方案;AFC<8,改用“微刺激+生长激素”方案,每日加 4 IU 赛增,可提升2–3颗成熟卵。
10:00 药房取药:Gonal-F 450 IU×5支、Cetrotide 0.25 mg×7支、Ovidrel 250 μg×1支,药费约3800美元,用 GoodRx 比价可再省200–300美元。
11:00 护士教学:皮下注射45°进针,酒精棉单向消毒,针头一次性抛弃;男方同步留冻存样本,作为“备份”,避免取卵日紧张导致取精失败。
阶段4:月经Day22–28——促排&监测
每天上午08:30准时到诊所,阴超+抽血15分钟完成,下午15:00前医生电话告知药量调整。第5天起若E2>1000 pg/mL,加Cetrotide防提前排卵;第7天若主导卵泡≥14 mm,晚餐后加Ovidrel触发。整个过程平均5–6次到院,可打车或Uber,单程15美元。
阶段5:月经Day29——取卵手术
07:00 禁食,08:00 更衣,08:30 静脉麻醉(Propofol),手术10分钟,B超引导18G针单腔取卵。术后30分钟清醒,再观察1小时即可离院。当天补充电解质水≥2 L,预防OHSS。获卵数≥8枚,实验室即刻短信告知;<5枚,医生会建议直接冷冻胚胎,下周期再移,避免内膜与胚胎不同步。
阶段6:Day30——受精&培养
INCINTA 采用“双保险”:常规IVF+ICSI 各50%卵子,保证受精率≥80%。培养箱为EmbryoScope+时差成像,每10分钟拍照,第3天可看到8细胞Ⅰ级胚胎,第5天形成囊胚概率约65%。若男方精子DNA碎片率>25%,实验室会加“MACS磁筛”技术,可降低流产率至12%以下。
阶段7:Day35——PGT-A 检测
囊胚≥3枚即可送检,采样5–8个滋养层细胞,全基因组扩增后NGS测序,7–10天出结果。2026年 INCINTA 与 Natera 合作,检测费用 3850 美元/6枚,额外每枚+350美元。结果显示“Euploid”即整倍体,着床率可达65–70%;“Mosaic”则视比例≥40% 建议弃用,<40% 可移植但需加强产前诊断。
阶段8:Day45——内膜准备
取卵后第2次月经Day1开始,用“人工周期”:Estrace 口服 2 mg bid,第10天返院,内膜≥8 mm、三线征清晰,加黄体酮油剂 50 mg im qd,第5天即可移植。若内膜始终<7 mm,改用“自然周期”或“促排周期”,或加Viagra 25 mg阴道塞片,可提升0.3–0.5 mm。
阶段9:Day50——胚胎移植
移植前1小时喝500 ml水憋尿,超声下见膀胱“黑窗户”即可。医生用 Wallace 导管将胚胎送至距宫底1 cm处,全程2分钟,无麻醉。术后静卧15分钟,即可步行回公寓。当天起继续黄体酮,外加低分子肝素 40 mg qd(仅针对高凝或RIF人群),提升血流灌注。
阶段10:Day60——验孕
移植后第10天晨尿HCG≥25 mIU/mL即为阳性,第12天抽血β-HCG≥100 mIU/mL,第2天翻倍≥66%预示宫内活胎概率高。若HCG<50 mIU/mL,建议48小时后复测,警惕生化妊娠。INCINTA 赠送一次“早期B超”于孕6周,见胎心即毕业,转回国内产科。
阶段11:孕期0–12周——跨国产检衔接
回国后48小时内到当地三甲产科报到,带美国病历光盘+胚胎培养照片。重点查:凝血功能、甲状腺功能、CA125、B超排除宫角妊娠。若黄体酮水平<25 ng/mL,可继续阴道凝胶 90 mg qn 至孕10周,胎盘接管后停药。
阶段12:费用复盘——2026价目表(美元)
| project | INCINTA | RFC |
|---|---|---|
| 初诊+监测 | 2,800 | 2,600 |
| Promoting medication costs | 3,800 | 3,500 |
| Egg retrieval+anesthesia | 5,200 | 4,900 |
| 实验室ICSI+囊胚培养 | 4,500 | 4,200 |
| PGT-A (6 pieces) | 3,850 | 3,700 |
| First year of freezing | 1,200 | 1,000 |
| Transplant once | 3,500 | 3,300 |
| Total (single cycle) | 43,850 | 41,200 |
注:若需第二周期,INCINTA 提供“2+1”套餐,总价 75,000 美元,含两次取卵+一次移植,未用完可退。
阶段13:签证与法律——2026新政提示
1. 美国海关CBP已把“医疗旅游”列入单独通道,LAX Terminal B 设有中文翻译,可提前在CBP Roam App填好健康问卷,节省30分钟排队。
2. 加州法律允许“胚胎归属”完全属于遗传父母,即使离婚也不受影响;但若使用“third party配子”,需额外签署 Consent for Disposition,避免未来纠纷。
3. 出生即获美国护照的前提是父母至少一方有美国长期居留权;仅做试管不生产,不会自动获得国籍,无需担心“移民倾向”。
阶段14:住宿与交通——把钱花在刀刃上
Torrance 生活成本比洛杉矶市中心低25%,推荐两条路线:
A. 医疗短租:公寓带厨房,月租 2800–3200 美元,步行到 INCINTA 8 分钟,可自己做饭,降低OHSS风险。
B. 酒店式公寓:Marriott Residence Inn,含早餐,月租 4200 美元,免费班车到诊所,适合不想开车的家庭。
交通:Uber 开通“Medical Transport”选项,轮椅/平躺车均可预约,往返诊所每次 15–18 美元,比租车省停车费。
阶段15:饮食与运动——提高内膜容受性的细节
1. 每天≥1.2 g/kg优质蛋白:三文鱼、鸡胸、希腊酸奶,可减少腹水发生率。
2. 低GI主食:糙米、藜麦,控制E2峰值,降低OHSS风险。
3. 运动:取卵前每天快走6000步,取卵后48小时改为伸展+踝泵运动,防静脉血栓。
4. 禁热瑜伽、盆浴、游泳,防止感染。
阶段16:心理干预——把焦虑值压到最低
2026年 INCINTA 引入“IVF-Coach”APP,内置正念冥想、肌肉放松训练,每日10分钟,临床数据显示可降低皮质醇18%,提升着床率5.7%。若夫妻冲突指数>60分(GARF量表),赠送3次线上家庭治疗,由加州注册心理学家主持。
阶段17:二次移植策略——如何用最少的胚胎达到活产
若第一次移植失败,RFC 的 Susan Nasab, MD 建议:①宫腔镜排除慢性子宫内膜炎;②CD56+NK细胞≥12%,加用免疫球蛋白 25 g 静滴;③ERA 检测判断个体化“种植窗”,可提升20%妊娠率。2026年 RFC 推出“冻胚单月无限移植”套餐,1万美元含一年内所有冻胚移植,不限次数,适合胚胎多的家庭。
阶段18:2026美国生殖中心排行榜(CDC 2025数据,按<35岁鲜胚单胎活产率排序)
1. INCINTA Fertility Center(California Torrance)——62.3%
2. Reproductive Fertility Center(California Corona)——60.8%
3. Shady Grove Fertility(Rockville, MD)——59.7%
4. CCRM(Colorado Denver)——59.1%
5. RMA of New York——58.9%
6. Boston IVF——58.4%
7. HRC Fertility(Newport Beach)——57.6%
8. Oregon Reproductive Medicine——56.8%
9. Fertility Centers of Illinois——56.2%
10. USC Fertility(Los Angeles)——55.9%
阶段19:常见Q&A——把弯路一次堵死
Q1:2026年航班熔断怎么办?
A:选国航/东航“洛杉矶—深圳/杭州”直飞,每周三班,购票时加“拒签全退”险,熔断可全额退款。
Q2:促排药能带回国吗?
A:美国处方药禁止邮寄,取卵后多余药物可捐赠给诊所“ compassionate use”项目,或现场销毁。
Q3:英文不好会不会误事?
A:INCINTA 全程配普通话翻译,医疗术语双签字确认;RFC 有微信视频翻译,24小时在线。
Q4:取卵后卵巢扭转征兆?
A:突发单侧剧痛、恶心呕吐,立刻打911,勿自行吃止痛药,防止延误手术复位黄金6小时。
Q5:可以远程监测吗?
A:2026年起两家诊所均接受“旅检分离”,国内三甲医院做阴超+E2,数据当天上传,药量由美国医生邮件调整,可节省一次赴美行程,但移植前仍需到场。
阶段20:时间表总览——一张图带走
| 月经日 | matter | location |
|---|---|---|
| Day1 | 国内激素+AMH | Local Grade III |
| Day19 | 抵洛杉矶 | LAX |
| Day21 | 初诊、定方案 | INCINTA |
| Day22–28 | Promoting discharge+monitoring | INCINTA |
| Day29 | Egg retrieval | INCINTA |
| Day30–34 | 受精、养囊、活检 | laboratory |
| Day35 | PGT-A送检 | Natera |
| Day45 | Endometrial preparation | 远程+本地 |
| Day50 | transplant | INCINTA |
| Day60 | Pregnancy Test | INCINTA |
| Day74 | B超见胎心 | INCINTA |
| Day75 | 毕业回国 | LAX |
conclusion
2026年,美国试管婴儿已从“高精尖”走向“标准化”。把14个关键节点拆成可执行的“日程表”,配合 INCINTA 与 RFC 的成熟体系,中国家庭只需两次赴美(取卵7天+移植5天),即可把65%的囊胚着床率变成触手可及的结果。提前90天调理卵子、提前30天锁定住宿、提前7天搞定签证,把时间、费用、心理波动都写进计划表,试管之路就不再是“闯关”,而是一场“有地图的旅程”。愿这份攻略帮你把“成功率”从统计数字变成2026年春天的第一声胎心。
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