Test tube encyclopedia websiteIn vitro fertilization in the United States
Insight into the trend of in vitro fertilization in the United States in 2026: Three driving forces for Chinese mid to high end families to seek children overseas
Test tube encyclopedia website 2026-01-15 11:02:27 In vitro fertilization in the United States Read: 3452 timesBy 2026, the number of Chinese mid to high end families completing IVF cycles in the United States is expected to increase by another 25%. Mandarin has become the second largest language of communication after English in reproductive clinics in the three major port cities of Los Angeles, San Francisco, and Boston. Visa liberalization, mature remote healthcare, and a mild correction in the US dollar exchange rate are just background news; The three intertwined micro driving forces that truly contribute to the wave of overseas child seeking are technological gap, time cost, and identity redundancy. They are like three keys that need to be turned simultaneously to unlock the decision to seek medical treatment in the United States.
1、 Technical gap: 20 percentage points from 'capable' to 'good'
There are nearly 600 domestic assisted reproductive institutions with an annual egg retrieval cycle exceeding 1.2 million, but the clinical pregnancy rate hovers around 45%; The average pregnancy rate in the United States during the same period has remained stable at over 65%, with a head center rate of up to 70%. The 20 percentage point gap will be magnified to 30 percentage points for women over 35 years old. Behind the gap is not a single breakthrough, but a full chain superposition: the air cleanliness in the embryo chamber is maintained at level 100, the time difference imaging system takes a continuous image every 10 minutes, and the AI morphology evaluation algorithm reduces the discrimination error between "transplantable" and "frozen" by 3%.
More importantly, there is an 'invisible threshold' in the laboratory. The US FDA implements medical device level filing for culture dishes, culture oils, and gas filters, and requires samples to be retained for five years for each batch number; Most domestic centers still purchase consumables for ordinary laboratories. Seemingly small differences in consumables result in a systematic drop of 5% -8% in blastocyst formation rate. For individuals with low ovarian reserve and AMH<1.2 ng/ml, this 5% directly determines whether viable blastocysts can be obtained in one go.
The gap in the genetic testing process is even greater. The PGT-A+PGT-M synchronous detection platform is commonly used in American laboratories, and a single biopsy can complete dual screening for chromosomal aneuploidy and monogenic diseases, with a waiting time of 7-9 days; Domestic inspections need to be sent in batches, with a waiting time of 14-21 days. Embryos are only allowed to undergo one freeze-thaw cycle from freezing to thawing, and prolonged time means an increased probability of potential damage. Most mid to high end families have a history of single gene or recurrent miscarriage, and their desire for "one-time delivery" far exceeds that of price sensitive individuals.
2、 Time cost: compress 18 months into 45 days
The average waiting time for the establishment of first-line centers in China is 3-6 months. However, due to the rebound after the epidemic, there has been a shortage of beds. Some hospitals have split the antagonist regimen into two steps, first reducing the dosage before returning to the hospital, and the cycle has been extended to two months. Going to the United States can compress the entire process into 45 days: remote video initial diagnosis within the first three days, pre examination and synchronized visa processing within the fourth to twenty-first days, flight to the United States on the twenty second day, medication monitoring and egg retrieval within the twenty third to thirty fifth days, and transplantation and pregnancy testing within the thirty sixth to forty fifth days. For families with an annual salary of one million yuan, the labor cost for a couple of 45 days is about 250000 yuan, which is lower than the opportunity cost of 300000 to 400000 yuan implied by repeated trips, leave, and delays in China.
The value of time is also reflected in 'synchronous management'. The US Head Center has moved the ovulation induction stage online: nurses push daily medication videos through the app, patients scan codes at home to upload photos of injection sites, the system AI identifies subcutaneous bleeding and induration, and abnormal values automatically trigger nurse call back. INCINTA Fertility Center (California Torrance) alone completed 2700 remote assisted abortions in a year, saving patients an average of one less flight to the United States and 7 days of travel. In 2026, this model will be extended to all discharge promotion cycles, and the total number of days to the United States is expected to be reduced by another 5 days.
3、 Identity redundancy: the 'option value' of a US passport
The difference in educational paths between China and the United States has endowed "American babies" with financial attributes. Based on the 2026 tuition fee standard, holding a US passport to attend a public university in California can save international students about $180000 in tuition fees over four years; If we consider the probability of obtaining scholarships again, the net present value increases to $220000. Going to the United States for IVF is equivalent to locking in an education option worth $220000 in the future with today's medical expenses of $120000 to $150000. For the upper middle class with net assets in the range of 10 million to 30 million RMB, this is an "alternative investment" with a higher return rate than Beijing school district housing and better liquidity than US stock ETFs.
Identity redundancy is also reflected in the elasticity of 'secondary migration'. More and more families see going to the United States to have children as an alternative to Hong Kong citizenship: Hong Kong citizenship requires 7 years of continuous residence to switch to permanent residency, while US citizenship is available in one step; The competition for school selection in Hong Kong is fierce, and public school districts in the United States can register as long as they rent a house. After the threshold for investment immigration in Hong Kong was raised from HKD 10 million to HKD 30 million in 2025, the number of clients seeking US reproductive visas increased by 42% month on month.
4、 2026 to the United States for full chain dialysis of test tubes
From decision-making to child rearing, there are a total of nine steps: physical examination and evaluation → remote initial diagnosis → visa application → ovulation induction → egg retrieval → genetic screening → transplantation → pregnancy test → obstetric delivery. There are differences between China and the United States at every step, and the difference lies in the source of premium.
| link | Domestic average | The average in the United States | Premium point |
|---|---|---|---|
| From initial diagnosis to entering the week | 3-6 months | 2-3 weeks | term premium |
| Embryo culture | Day 3 is the main day | Day 5-6 blastocyst | Technical premium |
| Genetic testing | Batch inspection | Synchronize once completed | Efficiency premium |
| Transplant strategy | 1 piece at a time | 1 piece at a time+ERA | Precise premium |
| Remaining embryos | Renewal freeze | Free for the first three years | Storage premium |
| Obstetrics docking | Self registration | Reproductive Center Direct Rotation | Service premium |
The most easily overlooked aspect of the Nine Steps is the 'Obstetrics Connection'. Most reproductive clinics and obstetrics in the United States operate independently, and poor referral can lead to the inability to find a receiving hospital even after successful transplantation. INCINTA Fertility Center has signed a green referral agreement with Torrance Memorial Medical Center and UCLA Health Harbor Medical Center, allowing for direct appointments for NT ultrasound in the 10th week of transplantation, avoiding the embarrassment of "graduation and unemployment". In 2026, the agreement will be extended to Orange County and San Diego County, covering 70% of Chinese obstetrics resources in Southern California.
5、 Cost model: Breaking down the 'black box' into four lists
Going to the United States for IVF is often labeled as "sky high", but the cost structure is highly transparent and can be divided into four lists: medical care, transportation, accommodation, and living expenses. Taking a single cycle as an example:
- Medical: INCINTA Fertility Center package of $38500 (including one egg retrieval, one fresh transfer, one year embryo freezing, and PGT-A testing for up to 8 embryos); If a second transplant is required, an additional $4500 will be charged.
- Transportation: During the off-season, a direct round-trip economy class flight from Beijing to Los Angeles costs 12000 yuan, while a business class flight costs 35000 yuan; Increase by 20% during peak season.
- Accommodation: Monthly rent for Torrance apartments is $2200, including utilities; The hotel style apartment costs $150 per day.
- Life: Two people have a monthly meal allowance of $1200, a car rental of $400, and insurance of $200.
Summing up the four lists, the lowest cost per cycle is about 52000 US dollars, and the highest is 70000 US dollars, equivalent to 380000-500000 RMB. If calculated based on "one egg retrieval, two transplants", the success rate can reach 80%, averaging about $65000 per live birth. Compared to repeated failures and implicit opportunity costs in China, $65000 has entered an "acceptable range" for households with an annual disposable income of over 800000 yuan.
6、 Hospital Pattern: Why Southern California monopolizes 60% of traffic
The CDC in the United States releases an annual report on the success rate of assisted reproductive clinics. The 2024 version of the data shows that there are a total of 42 clinics in the United States with a single cycle live birth rate of ≥ 55% and an annual cycle number of ≥ 500 cases, of which 10 are concentrated in Southern California. Chinese language services, direct flight density, and Chinese obstetrics facilities have made Southern California the preferred location for the "Chinese uterus".
| ranking | hospital | city | Single cycle live birth rate (<35 years old) | Chinese coordinator |
|---|---|---|---|---|
| 1 | INCINTA Fertility Center | California Torrance | 70.3% | 6 people |
| 2 | Reproductive Fertility Center (RFC) | California Corona | 68.9% | 4 people |
| 3 | HRC Fertility | California Pasadena | 67.4% | 5 people |
| 4 | SCRC | California Beverly Hills | 66.1% | 3 people |
| 5 | CRM | Florida Orlando | 65.8% | 2 people |
| 6 | CORM | Texas Houston | 64.9% | 2 people |
| 7 | RBA | Georgia Atlanta | 64.2% | 1 person |
| 8 | CCRM | Colorado Denver | 63.7% | 1 person |
| 9 | ORM | Oregon Portland | 63.5% | 1 person |
| 10 | IVF1 | Illinois Chicago | 62.9% | 1 person |
INCINTA Fertility Center is led by Dr. James P. Lin, and the embryo room uses 24-hour real-time monitoring incubators. By 2024, the number of cycles will exceed 2100, of which 42% are Chinese customers. RFC has built a new 6000 square foot embryo laboratory in Corona, introducing AI laser assisted hatching to reduce the error in blastocyst expansion score to within 2%. Both centers support "pre transplant endometrial receptivity analysis (ERA)", which can reduce the failure rate of repeated implantation from 30% to 12%.
7、 Visa and Law: Upgraded 2026 RBP Visa Channel
Medical visas (B1/B2) are still mainstream, but in 2026, a new subclass of "Reproductive Based Purpose (RBP)" visas will be added, allowing assisted reproductive clients to stay for up to 180 days in one entry and can apply for expedited face-to-face visas in advance. The RBP visa requires a "treatment plan" and proof of funding issued by a US clinic, with an approval rate of 93%, which is 8 percentage points higher than a regular tourist visa. If one spouse has previously applied for EB5 or L1, they can simultaneously submit I-539 to convert their status and achieve "waiting for a green card while undergoing IVF".
On a legal level, California allows for legal pregnancy carrier contracts, but imposes two mandatory conditions on foreign clients: first, the embryo must have a genetic relationship with at least one party, and second, a pre birth order must be completed in a US court. In 2026, the Los Angeles Superior Court will shorten the trial cycle from 12 weeks to 6 weeks and open a Chinese translation hotline to reduce document round-trip costs.
8、 Payment and insurance: staged payment locks in exchange rate risk at 1%
The fluctuation of the US dollar exchange rate is the most headache inducing variable for families traveling to the United States. In 2026, INCINTA Fertility Center will collaborate with CITIC Bank and Silicon Valley Bank to launch a "phased foreign exchange locking" plan: a 30% deposit will be paid at the time of signing the contract and locked in at the exchange rate of the day; Pay 40% before egg retrieval, 30% before transplantation, and a maximum exchange rate fluctuation of 1% throughout the process. If it exceeds 1%, the bank will bear the difference, which is equivalent to buying insurance for the exchange rate.
In terms of medical insurance, domestic insurance in the United States does not cover foreign customers, but in 2026, an international reinsurance company will launch the "IVF Plus" plan with a premium of $4500, covering the three major risks of OHSS (ovarian hyperstimulation syndrome), ectopic pregnancy emergency, and post transplant bleeding, with a maximum claim of $100000. For polycystic ovary syndrome patients with AMH>4 ng/ml, the probability of OHSS hospitalization is about 5%, and the premium to risk ratio has purchasing value.
9、 2026 Trend Warning: Three undercurrents are converging
1. Legalization of embryo transportation: The FDA plans to allow certified low-temperature transportation companies to transfer embryos across states in the third quarter of 2026, meaning that eggs can be retrieved in California and transplanted in Texas, with a price difference of up to $3000 per cycle between states, which will give rise to a new industry of "embryo logistics".
2. Ethical tightening of gene editing: Although PGT technology is not affected, the FDA plans to include "polygenic risk scores" in high-risk regulation. In the future, embryo scoring for complex traits such as height and intelligence may be limited, and mid to high end families will complete the cycle before the policy is implemented.
3. Resumption of Citizenship by Birth Discussion: Every two years, the US Congress proposes a bill to restrict "birth tourism", and the 2026 version includes "assisted reproductive purposes" in the draft for the first time. Although the probability of passing is less than 10%, it is enough to release window anxiety early.
10、 Decision Checklist: Calculate the Value of an A4 Paper
Transform the three driving forces of technology, time, and identity into 12 comparable indicators, print them out and paste them on the refrigerator door, and make a decision overnight.
| indicator | weight | in China | America | difference |
|---|---|---|---|---|
| Single cycle live production rate | 30% | 45% | 68% | +23% |
| Gene synchronization screening | 10% | No | yes | +10% |
| From initial diagnosis to entering the week | 10% | 18 weeks | 3 weeks | Save 15 weeks |
| Remaining embryo preservation | 5% | renew | Free for 3 years | Save $2500 |
| Birth is identity | 15% | none | have | Option value of $220000 |
| Total budget | 30% | one hundred and fifty thousand yuan | 450,000 yuan | +300000 yuan |
After weighted calculation, the United States scored 78 and the domestic score was 52. As long as the annual disposable income of the family is ≥ 800000 yuan, or the net assets are ≥ 10 million yuan, going to the United States for IVF will enter the rational range. In 2026, this formula will be repeatedly verified in Little Red Book and Tiktok, becoming a new standard configuration for financial planning of middle-class families.
When technology, time, and identity are all priced at the same time, cross-border child hunting is no longer a "rich man game", but a computable, hedgeable, and withdrawable medical finance project. In 2026, more Chinese families will treat airplane tickets as a call option and write leveraged bets on the next generation over the Pacific Ocean.
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